FIGURE

Fig. S6

ID

ZDB-FIG-120724-12

Publication

Flowers et al., 2012 - A zebrafish Notum homolog specifically blocks the Wnt/beta-catenin signaling pathway

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Fig. S6

Loss of Notum1a results in expanded Wnt reporter activity, but not bmp4, foxa, pax3a or pax6a expression. (A,B) Relative to that in uninjected controls (A), the domain of egfp expression in the tails of embryos in the Tg(TOP:dEGFP)^w26 reporter line is expanded in notum1a MO-injected embryos (B) at 24 hpf. (C-L) Transverse sections of neural tubes at 24 hpf. bmp4 (C,D), pax3a (E,F), pax6a (G,H), lhx3 (I,J) and foxa (K,L) are not affected in notum1a MO-injected embryos.

Expression Data

Gene:	EGFP
Fish:	w26Tg w26Tg + MO2-notum1a
Knockdown Reagent:	MO2-notum1a
Anatomical Term:	tail bud
Stage:	Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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