FIGURE

Fig. 4

ID
ZDB-FIG-120710-34
Publication
Carlin et al., 2012 - Six3 cooperates with Hedgehog signaling to specify ventral telencephalon by promoting early expression of Foxg1a and repressing Wnt signaling
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Fig. 4

Six3b is required during early segmentation to promote ventral telencephalic fates. (A-D) nkx2.1b (purple) and six3b (red) expression in control embryos (A), six3b;six7-deficient embryos (B), six3b;six7-deficient Tg(hsp70l:Gal4-VP16); Tg(UAS:six3b) embryos induced to misexpress six3b at tailbud stage (C) and six3b;six7-deficient Tg(hsp70l:Gal4-VP16); Tg(UAS:six3b) embryos induced to misexpress six3b at the 4-somite stage (D). (E-H) isl1 (purple) and six3b (red) expression in control embryos (E), six3b;six7-deficient embryos (F), six3b;six7-deficient Tg(hsp70l:Gal4-VP16); Tg(UAS:six3b) embryos induced to misexpress six3b at tailbud stage (G) and six3b;six7-deficient Tg(hsp70l:Gal4-VP16); Tg(UAS:six3b) embryos induced to misexpress six3b at the 6-somite stage (H). Arrows indicate the ventral telencephalon in 24 hpf embryos. Embryos are shown in lateral view with anterior towards the left. Red and green arrowheads indicate dorsal and ventral edges of the telencephalon, respectively. Scale bars: 100 μm.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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