Fig. 6
- ID
- ZDB-FIG-120601-62
- Publication
- Breau et al., 2012 - Chemokine and Fgf signalling act as opposing guidance cues in formation of the lateral line primordium
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Ectopic sources of Fgf10 attract SPCs. (A) hmx3 expression (purple) in embryos transplanted with Fgf10- or tdTomato-expressing cells (pink). Black, pink and white arrowheads show SPCs, transplanted cells and hmx3-expressing spinal cord neurons, respectively. Dashed lines represent the somitic midlines. z-focus made on the primordium and SPCs (a,b) and on the transplanted cells in the dorsal neural tube (c,d). (B) Distance between SPCs and the horizontal somitic midline in embryos with transplanted cells expressing Fgf10 (n=46) or tdTomato (n=38) dorsal to the primordium region. *P=0.010. See also supplementary material Fig. S3 and Materials and methods. Error bars represent s.e.m. Scale bars: 25 μm. |