FIGURE

Fig. 8

ID

ZDB-FIG-120525-61

Publication

Zhang et al., 2012 - beta-Catenin 1 and beta-catenin 2 play similar and distinct roles in left-right asymmetric development of zebrafish embryos

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Fig. 8

Effects of ctnnb1 and ctnnb2 knockdown in DFCs on DFCs-specific marker gene expression. Embryos at the 512-cell stage were injected and later examined for marker expression. (A-J) sox17 (A-E) and foxj1a (F-J) expression in DFCs at the 90% epiboly stage were unaltered in morphants. In the top right-hand corner of each picture are the number of embryos with the representative phenotype versus the total number of analyzed embryos. (K-O) tbx16 expression in DFCs at 75% epiboly stage was disrupted in morphants. Yellow arrows indicate the position of DFCs. (P-T) ntl expression in DFCs at 75% epiboly stage was impaired in morphants. Two-color in situ hybridization using ntl (red) and lft1 (dark purple) probes were performed. The expression domain of ntl in DFCs was indicated by white arrows. (P′-T′) Higher magnification images of the boxed areas in P-T. (U) Statistical data for ntl and tbx16 expression in DFCs. All embryos are shown as dorsal views with animal pole towards the top.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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