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General Information
ZIRC
ZFIN ID: ZDB-FIG-120316-73
Lee et al., 2012 - CEP41 is mutated in Joubert syndrome and is required for tubulin glutamylation at the cilium. Nature Genetics   44(2):193-199 Full text @ Nat. Genet.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Fish:
Anatomical Terms:
Stage Range: Shield to Pec-fin
PHENOTYPE:
Fish:
Knockdown Reagent:
Observed In:
Stage: Protruding-mouth

Fig. 2 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
cep41 WT standard conditions Shield whole organism ISH
5-9 somites Kupffer's vesicle ISH
20-25 somites brain ISH
20-25 somites immature eye ISH
20-25 somites inner ear ISH
20-25 somites pronephric duct ISH
Long-pec brain ISH
Long-pec eye ISH
Long-pec heart ISH
Long-pec inner ear ISH
Pec-fin brain ISH
Pec-fin eye ISH
Pec-fin heart ISH
Pec-fin inner ear ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-cep41 standard conditions Protruding-mouth brain hydrocephalic, abnormal
Protruding-mouth heart edematous, abnormal
Protruding-mouth post-vent region curved, abnormal
twu34Tg + MO1-cep41 standard conditions Protruding-mouth determination of heart left/right asymmetry disrupted, abnormal
Protruding-mouth heart inverted, abnormal
Full text @ Nat. Genet.