Fig. 5
- ID
- ZDB-FIG-120316-71
- Publication
- Brusegan et al., 2012 - ccdc80-l1 Is Involved in Axon Pathfinding of Zebrafish Motoneurons
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ccdc80-l1 is positively regulated by shh. (A–C) ccdc80-l1 expression in somites and myoseptum resulted strongly inhibited in embryos treated with 5 μM cyclopamine (asterisks in B), in comparison to control embryos at the same developmental stage (A). By converse, over-expression of shh led to an up-regulation of ccdc80-l1 in muscular territories (C). Expression in cranial ganglia (cg) was never perturbed. (D–F) ccdc80-l1 resulted slightly down-regulated in the muscles of heterozygous syu+/- mutants (E) in comparison to wild type siblings (D). A strikingly down-regulation was observed in homozygous syu-/- mutants (F). (A–C) Dorsal flat-mount preparations, anterior is up. (D–F) Lateral views of the tails, anterior is left. |
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Stage: | 14-19 somites |