FIGURE

Fig. 5

ID

ZDB-FIG-120315-69

Publication

Schaub et al., 2012 - Mutation of zebrafish Snapc4 is associated with loss of the intrahepatic biliary network

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Fig. 5

snRNA expression in s445 mutant larvae. (A) Real-time PCR to compare snRNA gene expression between wild-type and s445 mutant larvae at 100 hpf. Data are represented as fold change relative to expression levels in wild-type larvae. The expression levels of U1, U2, and U6 snRNAs are not significantly changed, while those of U4 (average 0.59 fold; s.d. = 0.22; p = 0.037) and U5 (average 0.36 fold; s.d. = 0.29; p = 0.024) snRNAs are down-regulated in s445 mutant larvae. *, p < 0.05; N.S., not significant (p > 0.05). (B) Northern blotting of snRNAs. Total RNA from wild-type and s445 mutant larvae at 100 hpf were blotted with snRNA probes to the indicated genes. A probe for the 28S ribosomal RNA was used as a loading control.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 363(1), Schaub, M., Nussbaum, J., Verkade, H., Ober, E.A., Stainier, D.Y., and Sakaguchi, T.F., Mutation of zebrafish Snapc4 is associated with loss of the intrahepatic biliary network, 128-137, Copyright (2012) with permission from Elsevier. Full text @ Dev. Biol.