FIGURE

Fig. 8

ID

ZDB-FIG-120312-8

Publication

Pack et al., 1996 - Mutations affecting development of zebrafish digestive organs

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Fig. 8

Pancreas mutants. Pancreas development in (A,C,E,G) wild type and (B,D,F,H) slj^m74 embryos. (A) Cross-section of the pancreas at 4 dpf showing islet (i) and exocrine (e) cells. (B) In slj^m74 the islet appears normal but the exocrine cells have not developed. (C) Immunoreactive insulin in the wild-type islet. (D) Immunoreactive insulin in the slj^m74 pancreas. (E) Immunoreactive carboxypeptidase A in the wild-type exocrine pancreas. (F) There is little if any immunoreactive carboxypeptidase A in the slj pancreas at 4 dpf. Arrrowheads mark the position of islet cells immunoreactive for insulin. Arrow, background staining in intestine. (G) GATA-5 in situ hybridization in the wild type shows expression in the exocrine pancreas (arrows). (H) slj^m74 does not express GATA-5 in the exocrine pancreas. Scale bars, A,B,D and F, 15 μm; C,E, 20 μm.

Expression Data

Gene:	gata5
Fish:	AB polr3b^m74/m74 (AB)
Anatomical Term:	exocrine pancreas
Stage:	Day 4

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	polr3b^m74/m74 (AB)
Observed In:	exocrine cell exocrine pancreas
Stage:	Day 4

Phenotype Detail

Acknowledgments

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