ZFIN Image: Pack et al., 1996, Fig. 8

Image

Figure Caption

Fig. 8 Pancreas mutants. Pancreas development in (A,C,E,G) wild type and (B,D,F,H) slj^m74 embryos. (A) Cross-section of the pancreas at 4 dpf showing islet (i) and exocrine (e) cells. (B) In slj^m74 the islet appears normal but the exocrine cells have not developed. (C) Immunoreactive insulin in the wild-type islet. (D) Immunoreactive insulin in the slj^m74 pancreas. (E) Immunoreactive carboxypeptidase A in the wild-type exocrine pancreas. (F) There is little if any immunoreactive carboxypeptidase A in the slj pancreas at 4 dpf. Arrrowheads mark the position of islet cells immunoreactive for insulin. Arrow, background staining in intestine. (G) GATA-5 in situ hybridization in the wild type shows expression in the exocrine pancreas (arrows). (H) slj^m74 does not express GATA-5 in the exocrine pancreas. Scale bars, A,B,D and F, 15 μm; C,E, 20 μm.

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Acknowledgments

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