FIGURE

Fig. 5

ID

ZDB-FIG-120206-11

Publication

Wiweger et al., 2012 - HSPG-Deficient Zebrafish Uncovers Dental Aspect of Multiple Osteochondromas

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Fig. 5

FGF8 stimulates growth of additional tooth-bud-like structures in ext2^-/- mutant.

Beads were implanted at 36–39 hpf on one side of the body into an area in between the heart, ear and pectoral fin, where the teeth start to form. At 5 dpf, fish were fixed and stained with Alizarin red. Tooth-buds-like structures were formed on the pharyngeal arch neighboured by FGF-coated bead (arrowhead). Opposite arch was not affected. The tooth-bud-like structures were observed on each side of ext2^-/--tooth. Asterisk indicate position of the bead.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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