FIGURE

Fig. S5

ID

ZDB-FIG-111102-41

Publication

Kur et al., 2011 - Loss of Lrp2 in zebrafish disrupts pronephric tubular clearance but not forebrain development

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Fig. S5

ATG morpholino knockdown of lrp2b in bugeye.

Bugeye embryos were injected with buffer (A, D) or with two different lrp2b ATG morpholinos (lrp2bMO1; lrp2bMO2) (B - F). In addition, all embryos received a test RNA encoding mCherry targeted by lrp2bMO1 and lrp2bMO2. Successful knockdown of mCherry expression was evaluated 3 hr after injection by whole mount fluorescence microscopy (A-C). Proper formation of head structure was documented at 24 hpf in lateral head aspects (D – F).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	lrp2a^mw1/mw1 lrp2a^mw1/mw1 + MO1-lrp2b lrp2a^mw1/mw1 + MO2-lrp2b
Knockdown Reagents:	MO1-lrp2b MO2-lrp2b
Observed In:	head
Stage:	Prim-5

Phenotype Detail

Acknowledgments

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