FIGURE

Fig. S1

ID

ZDB-FIG-111026-8

Publication

Smith et al., 2011 - Bmp and Nodal Independently Regulate lefty1 Expression to Maintain Unilateral Nodal Activity during Left-Right Axis Specification in Zebrafish

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Fig. S1

Formation of the cardiac atrioventricular canal is unaffected in bmpr1aa mutant embryos. (A,B) In situ hybridization for bmp4 in the heart of wild-type and bmpr1aa mutant embryos at 48 hpf. Bmp4 is expressed in the inflow region, atrioventricular (AV) canal (arrow) and outflow region of the heart. Although cardiac looping was affected in bmpr1aa mutant embryos, expression of bmp4 was unaffected. (C,D) In situ hybridization for tbx2b, which was expressed in the AV canal in wild-type siblings (C) and bmpr1aa mutant embryos (D). (E,F) In situ hybridization for has2, which was expressed in the endocardial cushion cells that will form the AV valves. Has2 expression was unaffected in bmpr1aa mutant embryos (F) compared to its wild-type siblings (E).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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