Fig. S6
Anatomical relationship between hindbrain vessels and the axonal scaffold. A-L, Maximum intensity confocal projections of immuno-fluorescently stained embryos carrying the endothelial-specific reporter Tg(kdrl:GFP)1a116. Endothelium, green (GFP). Axonal tracks, red (acetylated Tubulin). Ages (hpf) indicated above each column. Abbreviations (see Table 1): vasculature, white (apostrophe, right side); neuroepithelium, yellow. Small white arrows, CtAs. Small yellow arrows, neurons with axonal commissures. Yellow asterisk, r5 GFP-positive neuroepithelial signal from the Tg(kdrl:GFP)1a116 reporter. A-D, Dorsal views. Anterior, left. Left side, bottom. E-H, Left lateral views. Anterior, left. Dorsal, top. I-L, Transverse cross-sections of the hindbrain at the r5-r6 level. Dorsal, up. Left side, left. Scale bar (A), 100 μm. |
Reprinted from Developmental Biology, 357(1), Ulrich, F., Ma, L.H., Baker, R.G., and Torres-Vazquez, J., Neurovascular development in the embryonic zebrafish hindbrain, 134-51, Copyright (2011) with permission from Elsevier. Full text @ Dev. Biol.