FIGURE

Fig. 2

ID

ZDB-FIG-110811-8

Publication

Stoop et al., 2011 - Zebrafish embryo screen for mycobacterial genes involved in the initiation of granuloma formation reveals a newly identified ESX-1 component

Other Figures

All Figure Page

Back to All Figure Page

Fig. 2

Three out of 200 transposon mutants were identified as early granuloma mutants. Infection of embryos with mutants FAM53, FAM58 and FAM67 reproducibly resulted in either smaller or fewer early granulomas at 5 dpi, as compared with the wild type (see Fig. 1B). (A–C) Representative overlays of brightfield and fluorescent images of embryos infected with 71 CFUs of mutant FAM53 (A), 70 CFUs of mutant FAM58 (B) and 86 CFUs of mutant FAM67 (C) are shown. Scale bars: 500 μm. (D) Relative levels of infection determined by automated quantification of fluorescent pixels. The results represent mean + standard deviation of all experiments performed (n=3 to 9) (*P<0.029, ***P<0.001, unpaired Student’s t-test).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dis. Model. Mech.