FIGURE

Fig. 6

ID

ZDB-FIG-110811-10

Publication

Stoop et al., 2011 - Zebrafish embryo screen for mycobacterial genes involved in the initiation of granuloma formation reveals a newly identified ESX-1 component

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Fig. 6

Complementation of early granuloma mutant FAM58. Embryos 5 days after infection with wild-type Mma11, mutant FAM58 and FAM58 carrying a plasmid for expression of espL (C58a) or the espL-espB operon (C58b). (A–D) Representative images of embryos for all experiments performed (n=4 to 9) are shown. Infection doses were 137 CFUs for wild-type Mma11 (A), 128 CFUs for mutant FAM58 (B), 171 CFUs for C58a (C) and 127 CFUs for C58b (D). Scale bars: 500 μm. (E) Automated quantification of relative infection level. Results represent mean + standard deviation for all experiments performed (n=4 to 9) (***P<0.001, unpaired Student’s t-test).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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