FIGURE

Fig. 9

ID

ZDB-FIG-110712-60

Publication

Sedletcaia et al., 2011 - Heart chamber size in zebrafish is regulated redundantly by duplicated tbx2 genes

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Fig. 9

Cardiomyocyte proliferation is not decreased in the atrium of tbx2ab morphants. Embryos were pulse-labeled with bromodeoxyuridine (BrdU), and after being fixed, were co-stained to detect BrdU+ cells (green) and S46+ atrial cardiomyocytes (red). Hearts were imaged and the yellow (double positive) cells counted (examples indicated by the small arrows). A,B: The top panels show representative wild-type (A) and morphant (B) embryos at <32 hpf. C: The lower panel shows quantification of the average BrdU+ cardiomyocytes, in each case from several randomly chosen embryos, n = 4. According to Student′s t-test, P = 0.13. The result is consistent with the fact that the atrium is not altered in cell numbers.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB/TU + MO1-tbx2
Knockdown Reagent:	MO1-tbx2
Observed In:	atrium cardiac muscle cell
Stage:	Prim-15

Phenotype Detail

Acknowledgments

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