FIGURE

Fig. 5

ID

ZDB-FIG-110608-38

Publication

Popgeorgiev et al., 2011 - The Apoptotic Regulator Nrz Controls Cytoskeletal Dynamics via the Regulation of Ca(2)+ Trafficking in the Zebrafish Blastula

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Fig. 5

Nrz Knockdown Leads to Profound Alterations of the Cytoskeleton Inside the Yolk Cell

(A) F-actin staining in control embryos and nrz morphants at 40%?50% epiboly stage showing the status of cortical F-actin inside the vegetal pole (white asterisk). In nrz morphants, cortical actin is severely reduced or absent.

(B) Histogram showing the percentage of control embryos versus nrz morphants at 50% epiboly stage with normal (blue), reduced (red), or absent (green) cortical F-actin. See also Figure S4.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-bcl2l10
Knockdown Reagent:	MO1-bcl2l10
Observed In:	cortical actin cytoskeleton organization
Stage:	50%-epiboly

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Cell, 20(5), Popgeorgiev, N., Bonneau, B., Ferri, K.F., Prudent, J., Thibaut, J., and Gillet, G., The Apoptotic Regulator Nrz Controls Cytoskeletal Dynamics via the Regulation of Ca(2)+ Trafficking in the Zebrafish Blastula, 663-676, Copyright (2011) with permission from Elsevier. Full text @ Dev. Cell