FIGURE

Fig. S6

ID
ZDB-FIG-101105-6
Publication
Vermot et al., 2009 - Reversing blood flows act through klf2a to ensure normal valvulogenesis in the developing heart
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Fig. S6

Strong phenotype triggered by lidocaine treatment. (A) Control conditions (B) After treatment with lidocaine, 17% (n = 36) embryos do not have endothelial tissue thickening. (C and D) bmp4 expression in (C) lidocaine-treated and (D) untreated embryos. In treated embryos, the heart tube is very immature, a situation very similar to that observed in the no-flow conditions reported in [14]. Such embryos were not used for flow analyses or qPCR, nor were they tested for valve morphogenesis at later stages. White arrow points to the AV canal.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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