FIGURE

Fig. 2

ID

ZDB-FIG-101004-16

Publication

Dutton et al., 2001 - Zebrafish colourless encodes sox10 and specifies non-ectomesenchymal neural crest fates

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Fig. 2

cls phenotype is rescued by ectopic sox10 expression. Wild-type embryos show many large, strongly pigmented melanophores at 48 hpf (A; close-up of anal region in D), while hs>sox10(L142Q)-injected clsm618 mutants (B) show only tiny melanised spots in position of premigratory NCCs (arrowheads). (C,E,F) By contrast, clsm618 embryos injected with hs>sox10 and heat-shocked, show mosaic rescue of melanophores. This embryo showed one rescued melanophore in the dorsal stripe (* in C), two in the ventral stripe (arrows in C; close-up in E) and one on the yolk sac (F). Scale bar: 125 μm in A-C; 70 μm in D-F.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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