FIGURE

Fig. 5

ID

ZDB-FIG-100506-16

Publication

Nguyen et al., 2010 - The Paf1 complex component Leo1 is essential for cardiac and neural crest development in zebrafish

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Fig. 5

Pigmentation phenotypes of leo1^LA1186. (A, B) Gch is expressed in xanthophores of the head and trunk (A). Expression levels of gch are reduced in leo1^LA1186 mutants (B). (C, D) Dct, a marker for differentiated melanophores, is severely reduced in leo1^LA1186 mutants (D) compared to wild-type siblings (C). (E, F) Mitfa transcripts are detected in early melanoblasts along the head and trunk (E). Leo1^LA1186 mutants display a reduction in mitfa expression (F).

Expression Data

Genes:	dct gch2 mitfa
Fish:	WT leo1^{la1186/la1186}
Anatomical Terms:	head melanoblast head melanocyte head xanthophore trunk melanoblast trunk melanocyte trunk xanthophore
Stage:	Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	leo1^{la1186/la1186}
Observed In:	head melanoblast head melanocyte head xanthophore pigmentation trunk melanoblast trunk melanocyte trunk xanthophore
Stage:	Prim-5

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 341(1), Nguyen, C.T., Langenbacher, A., Hsieh, M., and Chen, J.N., The Paf1 complex component Leo1 is essential for cardiac and neural crest development in zebrafish, 167-175, Copyright (2010) with permission from Elsevier. Full text @ Dev. Biol.