Fig. S9
- ID
- ZDB-FIG-091113-127
- Publication
- Sanek et al., 2009 - Zebrafish zic2a patterns the forebrain through modulation of Hedgehog-activated gene expression
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Six3b depletion does not rescue the retinal patterning defect in Zic2a-depleted embryos. (A) Uninjected embryos show normal pax2a expression in the OS and ventral retina (33/33 embryos, n=2). (B) zic2a morphants exhibit ectopic expression of pax2a in the ventral retina (15/18 embryos, n=2). (C) six3b morphants show normal pax2a patterning (25/25 embryos, n=2). (D) Embryos co-injected with six3bMO and zic2aMO show ectopic pax2a expression in the retina similar to that observed in zic2a morphants (38/46 embryos, n=2). (E) A graphic summary of the pax2a rescue experiments. Red, expanded pax2a; blue, normal pax2a. Arrowheads point to the posterior limit of retinal pax2a expression. Lateral views with anterior to the left shown at prim-5. |