FIGURE

Fig. 7

ID

ZDB-FIG-090817-40

Publication

Huang et al., 2009 - Collagen IX is Required for the Integrity of Collagen II Fibrils and the Regulation of Vascular Plexus Formation in Zebrafish Caudal Fins

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Fig. 7

Vascular plexus causes wavy and fused fin rays in prp fish. (A–C) Blood vessel development in the caudal fin of wild-type (WT) fish. (D–F) Immunostaining of osteoblasts (red) with the ZnS5 monoclonal antibody of the same fins revealed that osteoblasts developed and were patterned after blood vessels as evidenced by areas where only blood vessels were present (arrows in panels D and E). (G) A prp fin showing the vascular plexus. (H) The same prp fin stained with ZnS5 (red) showing that the osteoblast pattern was closely associated with the blood vessel pattern. (I) High magnification of a representative area of (H) showing wavy and fused osteoblast rays along with the misconnected blood vessels (arrows).

Expression Data

Gene:	EGFP
Antibody:	zns-5
Fish:	y1Tg col22a1^j131/j131; y1Tg/y1Tg
Anatomical Terms:	caudal fin osteoblast caudal fin vasculature post-vent vasculature
Stage:	Days 14-20

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	col22a1^j131/j131; y1Tg/y1Tg
Observed In:	caudal fin interray vessel caudal fin osteoblast caudal fin morphogenesis
Stage:	Days 14-20

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 332(2), Huang, C.C., Wang, T.C., Lin, B.H., Wang, Y.W., Johnson, S.L., and Yu, J., Collagen IX is Required for the Integrity of Collagen II Fibrils and the Regulation of Vascular Plexus Formation in Zebrafish Caudal Fins, 360-370, Copyright (2009) with permission from Elsevier. Full text @ Dev. Biol.