FIGURE

Fig. S2

ID

ZDB-FIG-090804-51

Publication

Drerup et al., 2009 - Disc1 regulates foxd3 and sox10 expression, affecting neural crest migration and differentiation

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Fig. S2

Pharyngeal arch CNC populations were reduced in Disc1 morphants. (A,B,D,E) dlx2a expression, marking the neural crest population in these structures, is reduced in the pharyngeal arches of Disc1 morphants (double-headed arrows). (G-L) Similarly, hand2 expression was dramatically reduced or lost in the pharyngeal arches at 26 hpf, 30 hpf, and 32 hpf in Disc1 morphants (arrow marks first arch; arrowhead marks posterior arches). (C,F) Pharyngeal arch (P1-P7) development was also reduced at 32 hpf in Tg(sox10:egfp) zebrafish. All views are dorsal with anterior to the left, except for C and F, which are lateral views.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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