FIGURE

Fig. S3

ID
ZDB-FIG-090618-29
Publication
Yuan et al., 2009 - The mob as tumor suppressor (mats1) gene is required for growth control in developing zebrafish embryos
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Fig. S3

Phenotypes of mats1 morphants were not caused by off-target p53 activation. (A) The mats1/p53 morphant embryos still exhibited the developmental delay phenotype. Embryos injected with 17 ng p53 MO didn’t show any abnormal phenotype. When coinjected with 17 ng p53 MO plus 8.5 ng mats1 MO2, the severe developmental delay phenotype still exist, but the small, dark, necrotic heads phenotype was lessened. (B) The mats1/p53 double knockdown embryos still exhibited excessive apoptosis as demonstrated by TUNEL staining, with decreased signal in head region. Anterior is towards left and dorsal towards top in all panels.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Knockdown Reagents:
Observed In:
Stage: Prim-5

Phenotype Detail
Acknowledgments
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