FIGURE

Fig. S3

ID

ZDB-FIG-090618-29

Publication

Yuan et al., 2009 - The mob as tumor suppressor (mats1) gene is required for growth control in developing zebrafish embryos

Other Figures

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Fig. S3

Phenotypes of mats1 morphants were not caused by off-target p53 activation. (A) The mats1/p53 morphant embryos still exhibited the developmental delay phenotype. Embryos injected with 17 ng p53 MO didn’t show any abnormal phenotype. When coinjected with 17 ng p53 MO plus 8.5 ng mats1 MO2, the severe developmental delay phenotype still exist, but the small, dark, necrotic heads phenotype was lessened. (B) The mats1/p53 double knockdown embryos still exhibited excessive apoptosis as demonstrated by TUNEL staining, with decreased signal in head region. Anterior is towards left and dorsal towards top in all panels.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-mob1a + MO4-tp53
Knockdown Reagents:	MO1-mob1a MO4-tp53
Observed In:	apoptotic process embryo development
Stage:	Prim-5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Dev. Biol.