FIGURE

Fig. S1

ID

ZDB-FIG-090504-23

Publication

Mich et al., 2009 - Germ cell migration in zebrafish is cyclopamine-sensitive but Smoothened-independent

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Fig. S1

Cyclopamine induces PGC mislocalization during gastrulation and early somitogenesis. (A–B) Distribution of vasa-expressing PGCs and sdf1a transcripts in shield-stage (6 hpf) embryos treated with either ethanol or cyclopamine, starting from the one-cell stage. (C–D) Corresponding analysis of embryos at the 3-somite stage (11 hpf). Scale bars: 100 μm. (E) Quantification of PGC mislocalization in ethanol- or cyclopamine-treated embryos at various developmental time points. At least 400 PGCs were scored as either within or outside of the sdf1a expression domain for each experimental condition.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 328(2), Mich, J.K., Blaser, H., Thomas, N.A., Firestone, A.J., Yelon, D., Raz, E., and Chen, J.K., Germ cell migration in zebrafish is cyclopamine-sensitive but Smoothened-independent, 342-354, Copyright (2009) with permission from Elsevier. Full text @ Dev. Biol.