FIGURE

Fig. 5

ID

ZDB-FIG-090320-40

Publication

Sims Jr et al., 2009 - Connexin43 regulates joint location in zebrafish fins

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Fig. 5

The cx43 mRNA is overexpressed in alf^dty86 fins. (A, B) Whole mount in situ hybridization shows that the distal expression domain of cx43 is expanded in alf^dty86 fins. (C, D) The expansion of the mesenchymal cx43 expression domain is also apparent following cryosectioning of stained fins. (E) The length of the cx43 expression domain was measured from the V + 3 fin ray in each of ten fins, and is statistically different between alf^dty86 and wild-type fins.

Expression Data

Gene:	gja1b
Fish:	WT kcnk5b^ty86d/+
Anatomical Term:	fin
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	kcnk5b^ty86d/+ + MO2-gja1b
Knockdown Reagent:	MO2-gja1b
Observed In:	embryonic skeletal joint morphogenesis fin
Stage:	Adult

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 327(2), Sims Jr, K., Eble, D.M., and Iovine, M.K., Connexin43 regulates joint location in zebrafish fins, 410-418, Copyright (2009) with permission from Elsevier. Full text @ Dev. Biol.