FIGURE

Fig. 8

ID

ZDB-FIG-090313-19

Publication

Blader et al., 1998 - Ethanol impairs migration of the prechordal plate in the zebrafish embryo

Other Figures

All Figure Page

Back to All Figure Page

Fig. 8

Expression of anterior midline markers in ethanol-treated embryos. (A and B) Control (A) and ethanol-treated embryos hybridized to hgg-1 (hg) and pax-2 (p) probes. (C and D) otx-2 expression in control (C) and ethanol-treated embryos (D) stained with otx-2 probe. Arrow indicates otx-2 expression in the posteriorly displaced prechordal plate in the ethanol-treated embryo (D). (E to G) Control (E) and ethanol-treated embryos (F, G) labeled with isl-1 (i) and pax-2 (p) probes. (H to L) Control (H) and ethanol-treated embryos stained with hlx-1 (h) and pax-2 probes (p). hlx-1 expression is impaired anterior to the pax-2 expression domains, but unlike hgg-1 (B) and isl-1 (C) hlx-1 transcripts are not detectable posterior to the pax-2 stripes (L, arrowhead). (M to P) Control (M) and ethanol-treated embryos (N to P) stained with shh (s) and pax-2 probes (p). Ethanol-treated embryos show progressive loss of anterior shh expression, while expression of shh posterior to the pax-2 stripes is unaffected in treated embryos. Embryos are at the 100% epiboly stage and are shown in dorsal views with anterior up.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 201, Blader, P. and Str�hle, U., Ethanol impairs migration of the prechordal plate in the zebrafish embryo, 185-201, Copyright (1998) with permission from Elsevier. Full text @ Dev. Biol.