FIGURE

Fig. 6

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ZDB-FIG-090313-17

Publication

Blader et al., 1998 - Ethanol impairs migration of the prechordal plate in the zebrafish embryo

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Fig. 6

Ethanol treatment impairs migration of prechordal plate cells. (A to D) Control embryo (A) and ethanol-treated embryos (B to D) at the 100% epiboly stage. Embryos were simultaneously stained with gsc (g) and pax-2 (p) probes. In most cases, gsc-expressing cells formed a cluster which was retarded in its anterior migration (B, C). Less frequently, the gsc expression domain (g) was split in the ethanol-treated embryo (D). (E to H) Control and ethanol-treated embryos stained with gsc and pax-2 antisense probes (blue) and anti-Ntl antibody (brown). The expression domains of gsc (g), pax-2 (p), and Ntl (N) are indicated; gsc expression in G is out of the plane of focus. Open triangles in F and H indicate planes of sections shown in Figs. 7B and 7A, respectively. Orientation of embryos is anterior up and view is from the dorsal aspect.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 201, Blader, P. and Str�hle, U., Ethanol impairs migration of the prechordal plate in the zebrafish embryo, 185-201, Copyright (1998) with permission from Elsevier. Full text @ Dev. Biol.