FIGURE
Fig. 4
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- ZDB-FIG-081014-3
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- Lewis et al., 1999 - Characterisation of a second patched gene in the zebrafish Danio rerio and the differential response of patched genes to hedgehog signalling
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Fig. 4
ptc expression in cyclops homozygotes. Transcripts were revealed by in situ hybridisation with antisense RNA probes to shh (A and E), twhh (B and F), ptc2 (C and G), and ptc1 (D and H). (E–H) show expression in cyclops homozygotes and (A–D) show expression in wild-type siblings processed in parallel. All embryos were fixed at 24 hpf. Expression of both ptc genes is lost from all the areas of the anterior brain except for cells around the cells still expressing shh and/or twhh. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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Reprinted from Developmental Biology, 208, Lewis, K.E., Concordet, J.P., and Ingham, P.W., Characterisation of a second patched gene in the zebrafish Danio rerio and the differential response of patched genes to hedgehog signalling, 14-29, Copyright (1999) with permission from Elsevier. Full text @ Dev. Biol.