FIGURE

Fig. 8

ID

ZDB-FIG-081013-25

Publication

Harris et al., 2008 - Zebrafish eda and edar mutants reveal conserved and ancestral roles of ectodysplasin signaling in vertebrates

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Fig. 8

Eda signaling is required for the function of the fin fold during late fin development.

Expression of bmp2b (A), shh (B) and edar (C) transcripts in developing juvenile (8 mm, 30 dpf) fin rays of the caudal fin; asterisks indicate regional expression within distal tip of developing ray; arrows in (C), expression in distal epidermis of the fin fold. D–I) Histological analysis of both paired (pectoral, D, E) and unpaired fins (anal F, G; and caudal, H, I) from fls^te370f and wild type siblings. fls^te370f fins showed a general deficiency in the maturation of the muscle and dermis of the fin (arrow G; acellular debris in anal fin of fls). Insets (D, E), tip of fin at higher magnification showing degeneration of the nuclei of the epidermis in the mutant fin. ffd, fin fold; le, lepidotrichia of the fin rays.

Expression Data

Genes:	bmp2b edar shha
Fish:	WT
Anatomical Term:	caudal fin lepidotrichium
Stage:	Days 21-29

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	edar^{te370f/te370f} (TU)
Observed In:	anal fin mesoderm caudal fin mesoderm
Stage:	Days 21-29

Phenotype Detail

Acknowledgments

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