FIGURE

Fig. 3

ID

ZDB-FIG-080826-11

Publication

Mizoguchi et al., 2008 - Sdf1/Cxcr4 signaling controls the dorsal migration of endodermal cells during zebrafish gastrulation

Other Figures

(all 11)

All Figure Page

Back to All Figure Page

Fig. 3

Sdf1 acts as a chemoattractant for cxcr4a-expressing endodermal cells. (A) Schematic representation of the cell-transplantation approach. nlacZ, sdf1a or sdf1b mRNA was co-injected with dextran-Alexa594 into WT donor zebrafish embryos at the one-cell stage. Donor cells from dome-stage embryos were placed in the ventrolateral margin of sdf1MOs-injected host embryos at the shield stage. (B-J) Lateral views of a Tg(sox17:EGFP) transgenic embryo with anterior to the top, at TB stage. V, ventral; D, dorsal. (B-D) nlacZ-expressing donor cells do not attract the EGFP-expressing endodermal cells. (E-J) EGFP-expressing endodermal cells are attracted to the cluster of sdf1a- or sdf1b-expressing cells, which are labeled with dextran-Alexa594 (red).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development