FIGURE

Fig. 1

ID
ZDB-FIG-080731-4
Publication
Sultana et al., 2008 - Zebrafish early cardiac connexin, Cx36.7/Ecx, regulates myofibril orientation and heart morphogenesis by establishing Nkx2.5 expression
Other Figures
All Figure Page
Back to All Figure Page
Fig. 1

Progressive heart malformation in zebrafish ftk mutant. (A and B) Gross heart morphology of ftk mutant. Wild-type (A) and ftk mutant embryos (B) at 74 hpf. Arrowhead indicates heart perforations in the ftk mutant; arrow points to blood cells accumulated in the pericardiac cavity. (C–F) Sagittal sections of the heart. At 72 hpf (C and D), a dilated atrium (A) and ventricle (V) are evident in the ftk mutant. The cardiac muscles appear to be thinner (arrows in D), and the dilation of heart chambers is under way. At 120 hpf (E and F), the heart chamber dilation becomes more severe in ftk mutants with thinner ventricular and atrial walls. Red arrows indicate the valve leaflets. (Scale bars: 150 μm.)

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Observed In:
Stage Range: Protruding-mouth to Day 5

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA