FIGURE

Fig. 1

ID

ZDB-FIG-080604-57

Publication

Zhang et al., 2008 - Cell cycle progression is required for zebrafish somite morphogenesis but not segmentation clock function

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Fig. 1

tiy121 mutants have a cell cycle defect. (A-D) Phosphorylated Histone H3 staining (PHH3, red) marks mitotic cells in wild-type embryos at the shield (A) and 10-somite stage (C). No mitotic nuclei are seen in tiy121 embryos at the shield (B) or 10-somite stage (D). Nuclei are stained with DAPI (blue). (E,F) Wild-type (E) and tiy121^-/- (F) embryos at 30 hpf. (G,H) BrdU labeling (red) in the trunks of wild type (G) and tiy121^-/- (H) at the 14-somite stage. Asterisks label the notochord. BrdU was injected into the yolk at the 8-somite stage. In C-F, anterior is left; in G and H, anterior is up.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	fbxo5^{tiy121/tiy121}
Observed In:	mitotic cell cycle pericardium whole organism
Stage Range:	Shield to Protruding-mouth

Phenotype Detail

Acknowledgments

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