FIGURE

Fig. 2

ID

ZDB-FIG-080507-12

Publication

Watson et al., 2008 - The endocannabinoid receptor, CB1, is required for normal axonal growth and fasciculation

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Fig. 2

Maturation of CB1 expression in the spinal cord. (A–C) Sections of the spinal cord at the forelimb levels at stage 20. (A) Isl1 is expressed in the forming motor neurons and in the condensing DRGs. (B) Lack of CB1 expression. (C) Hu immunoreactivity in the mature motor neurons. (D–F) Sections of the spinal cord at forelimb level at stage 25. (D) Isl1 expression in the motor neurons, dorsal interneurons, DRGs and sympathetic ganglia. (E) CB1 expression in interneurons and DRGs and sympathetic ganglia. (F) Hu immunohistochemistry labels many neuronal populations in the spinal cord, and also the DRGs and sympathetics. (G–I) Sections of the spinal cord at the forelimb level at stage 29. (G) Isl1 is expressed by motor neurons, DRGs and sympathetic ganglia. (H) CB1 is expressed in many neuronal populations in the spinal cord and also in the DRGs. (I) Hu immunoreactivity labels many neurons in the spinal cord and the DRG. ^* indicates the position of the DRGs, MN—motor neurons, S—sympathetic ganglia.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

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Acknowledgments

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Reprinted from Molecular and cellular neurosciences, 38(1), Watson, S., Chambers, D., Hobbs, C., Doherty, P., and Graham, A., The endocannabinoid receptor, CB1, is required for normal axonal growth and fasciculation, 89-97, Copyright (2008) with permission from Elsevier. Full text @ Mol. Cell Neurosci.