FIGURE

Fig. S5

ID

ZDB-FIG-080422-16

Publication

Chung et al., 2008 - Intra-endodermal interactions are required for pancreatic beta cell induction

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Fig. S5

Induction of Tg(ins:GFP) Expression in smo Mutants Is Coincidental with Close Contact with Wildtype Endodermal Cells
(A and B) Transverse confocal images of smo mutant host stained for GFP (green; A and B) and β-catenin (white; A) at 18 hpf. Wildtype donor cells are labeled with rhodamine dextran (red). ([A] and [B]) show the same embryo. (A) During the transplantation experiments shown in Figure S4 and Table S1B, we found one embryo in which Tg(ins:GFP) expression in smo mutant endoderm was rescued (arrow) when wildtype donor cells were incorporated into the endoderm directly adjacent to the rescued Tg(ins:GFP) expressing mutant cell. (B) Magnified view of the rescued Tg(ins:GFP) expressing mutant cell (arrow) shown in (A).

Expression Data

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Antibody Labeling

Phenotype Data

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Acknowledgments

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Reprinted from Developmental Cell, 14(4), Chung, W.S., and Stainier, D.Y., Intra-endodermal interactions are required for pancreatic beta cell induction, 582-593, Copyright (2008) with permission from Elsevier. Full text @ Dev. Cell