FIGURE

Fig. 5

ID

ZDB-FIG-080326-122

Publication

Bonner et al., 2008 - Proliferation and patterning are mediated independently in the dorsal spinal cord downstream of canonical Wnt signaling

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Fig. 5

Transcriptional activation by Lef/Tcf factors mediates progenitor patterning in the spinal cord. (A, B) Expression of msxc and (C, D) pax3 is reduced in ΔTcf-expressing embryos. (E, F) Expression of dbx2 shifts into the dorsal domain of the spinal cord in ΔTcf-expressing embryos, and is ectopically present in the somites. (G, H) Expression of nkx6.2 is unaffected in ΔTcf-expressing embryos. (A?D, G, H) Lateral mounts are shown. (E, F) 12 μm cross-sections are shown. Scale bars = 10 μm.

Expression Data

Genes:	dbx2 msx3 nkx6.2 pax3a
Fish:	WT w26Tg/+
Condition:	heat shock
Anatomical Terms:	somite spinal cord
Stage:	Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 313(1), Bonner, J., Gribble, S.L., Veien, E.S., Nikolaus, O.B., Weidinger, G., and Dorsky, R.I., Proliferation and patterning are mediated independently in the dorsal spinal cord downstream of canonical Wnt signaling, 398-407, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.