FIGURE

Fig. 5

ID

ZDB-FIG-071015-13

Publication

Stickney et al., 2007 - Zebrafish bmp4 functions during late gastrulation to specify ventroposterior cell fates

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Fig. 5

Blood fate is first expanded and then reduced upon progressive loss of BMP activity. gata1 expression at 10 somites in embryos from a cross between a triple bmp heterozygote and a bmp4^st72 heterozygote. (A) Wild-type phenotype exhibited by a bmp4^st72 heterozygote. Expansion of the gata1 expression domain ventral to the tailbud is evident in a bmp4^st72 homozygote (B) and a bmp4^st72/bmp4^st72; snh^ty68a/+ embryo (C). Reduction of the gata1 expression domain is observed upon further reduction of BMP, as in these bmp4^st72/bmp4^st72; swr^ta72/+ (D) and bmp4^st72/bmp4^st72; snh^ty68a/+; swr^ta72/+ (E) embryos, although ectopic gata1 expression ventral to the tailbud is still apparent.

Expression Data

Gene:	gata1a
Fish:	bmp4^st72/st72 bmp4^st72/+ bmp2b^ta72a/+; bmp4^st72/st72 bmp4^st72/st72; bmp7a^ty68a/+ bmp2b^ta72a/+; bmp4^st72/+; bmp7a^ty68a/+
Anatomical Terms:	mesoderm tail bud
Stage:	10-13 somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 310(1), Stickney, H.L., Imai, Y., Draper, B., Moens, C. and Talbot, W.S., Zebrafish bmp4 functions during late gastrulation to specify ventroposterior cell fates, 71-84, Copyright (2007) with permission from Elsevier. Full text @ Dev. Biol.