FIGURE

Fig. 2

ID
ZDB-FIG-070823-22
Publication
Carl et al., 2007 - Wnt/Axin1/beta-Catenin Signaling Regulates Asymmetric Nodal Activation, Elaboration, and Concordance of CNS Asymmetries
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Fig. 2

The mbl Mutation Can Activate Epithalamic Nodal Pathway Genes Epistatic to Loss of Spw Activity (A) The graph illustrates the percentage of embryos with wild-type (WT) left, reversed (rev) right, bilateral (bil), or not visible (nv) Nodal pathway gene expression in the epithalamus of wild-type (mbl sib) mbl (mbltm213/tm213), spw morphant (MoSpw/mbl sib), and mbl;spw morphant (MoSpw/mbl) embryos. The knockdown of Spw function results in the absence of lft1 and pitx2 expression only in the presence of wild-type Axin1. (B?E) Frontal views of the epithalamus (dorsal to the top) of 24s stage wild-type (mbl sib) mbl, spw morphant (MoSpw/mbl sib), and mbl;spw morphant (MoSpw/mbl) embryos analyzed for lft1 expression.

Expression Data
Gene:
Fish:
Knockdown Reagent:
Anatomical Term:
Stage: 20-25 somites

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Knockdown Reagent:
Observed In:
Stage: 20-25 somites

Phenotype Detail
Acknowledgments
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