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General Information
ZIRC
ZFIN ID: ZDB-FIG-070620-38
Holtzman et al., 2007 - Endocardium is necessary for cardiomyocyte movement during heart tube assembly. Development (Cambridge, England)   134(13):2379-2386 Full text @ Development
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Observed In:
Stage: 20-25 somites

Fig. 4 Endocardium directs cardiomyocyte movement, even in the absence of initial medial movement. (A-D) Selected images from a time-lapse of cardiac fusion in a mil;clo double-mutant zebrafish embryo expressing Tg(cmlc2:egfp) (see Movie 4 in the supplementary material), exhibiting cardiac morphology at the (A) 19-somite and (B) 23-somite stages. Dorsal views, anterior to the top. (C,D) Paths traveled by cardiomyocytes in the right lateral heart field during the entire time-lapse (asterisks as described in Fig. 1). Images in C,D are three times the magnification of those in A,B. Scale bar: 20 μm. Example shown is representative of four heart fields analyzed. Cardiomyocytes in mil;clo double mutants exhibit no net directed movement.

Gene Expression DetailsNo data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
npas4ls5/s5; s1pr2te273/te273; twu34Tg standard conditions 20-25 somites heart rudiment malformed, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Development (Cambridge, England) for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Development