header logo image header logo text
Downloads Login
General Information
ZFIN ID: ZDB-FIG-070620-38
Holtzman et al., 2007 - Endocardium is necessary for cardiomyocyte movement during heart tube assembly. Development (Cambridge, England)   134(13):2379-2386 Full text @ Development
Observed In:
Stage: 20-25 somites

Fig. 4 Endocardium directs cardiomyocyte movement, even in the absence of initial medial movement. (A-D) Selected images from a time-lapse of cardiac fusion in a mil;clo double-mutant zebrafish embryo expressing Tg(cmlc2:egfp) (see Movie 4 in the supplementary material), exhibiting cardiac morphology at the (A) 19-somite and (B) 23-somite stages. Dorsal views, anterior to the top. (C,D) Paths traveled by cardiomyocytes in the right lateral heart field during the entire time-lapse (asterisks as described in Fig. 1). Images in C,D are three times the magnification of those in A,B. Scale bar: 20 μm. Example shown is representative of four heart fields analyzed. Cardiomyocytes in mil;clo double mutants exhibit no net directed movement.

Gene Expression DetailsNo data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
npas4ls5/s5; s1pr2te273/te273; twu34Tg standard conditions 20-25 somites heart rudiment malformed, abnormal
ZFIN wishes to thank the journal Development (Cambridge, England) for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Development