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General Information
ZFIN ID: ZDB-FIG-070619-1
Wang et al., 2006 - DNA Repair Protein Involved in Heart and Blood Development. Molecular and cellular biology   26(23):9083-9093 Full text @ Mol. Cell. Biol.
Knockdown Reagents:
Observed In:
Stage Range: High to Day 5

Fig. 6 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression DetailsNo data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-apex1 + MO2-apex1 + MO3-apex1 standard conditions Day 5 blood circulation disrupted, abnormal
Day 5 brain deformed, abnormal
Day 5 endocardial cushion present, normal
Day 5 eye decreased size, abnormal
Day 5 heart deformed, abnormal
Day 5 heart looping disrupted, abnormal
Day 5 nucleate erythrocyte decreased amount, abnormal
Day 5 pericardium edematous, abnormal
WT + MO4-apex1 standard conditions High whole organism lethal (sensu genetics), abnormal
twu34Tg + MO4-apex1 standard conditions Protruding-mouth cell death increased occurrence, abnormal
Protruding-mouth heart looping disrupted, abnormal
Full text @ Mol. Cell. Biol.