FIGURE
Fig. 4
- ID
- ZDB-FIG-070608-8
- Publication
- Hall et al., 2007 - The zebrafish candyfloss mutant implicates extracellular matrix adhesion failure in laminin {alpha}2-deficient congenital muscular dystrophy
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Fig. 4
Immunohistochemistry at 72 hpf shows retraction of epitopes with detaching fibers, demonstrating that failure occurs within the extracellular matrix rather than at the sarcolemma. (A) caf, anti-dystrophin. (B) Wild-type anti-dystrophin. (C) caf, anti-β-dystroglycan. (D) Wild-type anti-β-dystroglycan. (E) caf, anti-laminin 1. (F) Wild-type anti-laminin 1. (i) Flourescence, (ii) DIC, and (iii) merge. Arrowheads indicate retraction of epitopes with individual fibers. Images show lateral views, anterior to the left. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Observed In: | |
| Stage: | Protruding-mouth |
Phenotype Detail
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Full text @ Proc. Natl. Acad. Sci. USA