FIGURE

Fig. 5

ID

ZDB-FIG-070608-16

Publication

Schäfer et al., 2005 - Hedgehog and retinoid signalling confines nkx2.2b expression to the lateral floor plate of the zebrafish trunk

Other Figures

All Figure Page

Back to All Figure Page

Fig. 5

Differential regulation of nkx2.2b expression in hedgehog mutants. nkx2.2b expression in wild-type (A,B), yot (C,D), dtr (E,F), syu (G,H) and smu (I,J) 18s stage embryos. Left panel is lateral overview of embryos, right panels are dorsal views of trunk region. Small insets in left panel show lateral views of wild-type siblings from same clutch of heterozygous carriers. Note gradual loss of nkx2.2b expression in head regions of homozygous mutants. Arrowheads indicate areas with loss of nkx2.2b expression. Scale bar in (I) represents 200 µm (for A,C,E,G,I) and in (J) 30 µm (for B,D,F,H,J).

Expression Data

Gene:	nkx2.2b
Fish:	Df(Chr07)t4/t4 WT gli1^{te370a/te370a} gli2a^ty17a/ty17a smo^b641/b641 (AB)
Anatomical Terms:	head hindbrain lateral floor plate midbrain rhombomere trunk (all 6)
Stage:	14-19 somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Mechanisms of Development, 122(1), Schäfer, M., Kinzel, D., Neuner, C., Schartl, M., Volff, J.N., and Winkler, C., Hedgehog and retinoid signalling confines nkx2.2b expression to the lateral floor plate of the zebrafish trunk, 43-56, Copyright (2005) with permission from Elsevier. Full text @ Mech. Dev.