FIGURE

Fig. 4

ID

ZDB-FIG-070412-7

Publication

Yan et al., 2002 - A zebrafish sox9 gene required for cartilage morphogenesis

Other Figures

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Fig. 4

Splice-directed morpholinos to sox9a produce a phenotype similar to jef. (A-C) Uninjected wild-type controls. (D-F) Homozygous wild types injected with MO i1d plus i2d. (G-I) Heterozygotes for jef^tw37 injected with MOs. (J-L) MO injected homozygous jef^tw37 individuals. (A,D,G,J) Lateral view of 5 dpf animals, anterior towards the left. (B,E,H,K) Ventral view of dissected cartilages, anterior towards the left. (C,F,I,L) Right pectoral and fin skeleton, proximal towards the left. bh, basihyal; bsr, branchiostegal rays; cb, ceratobranchials; ch, ceratohyal; ch?, presumed ceratohyal; cl, cleithrum; ed, endoskeletal disk; co, scapulocoracoid; hs, hyosymplectic; m, Meckel?s cartilage; m/de? putative Meckel?s cartilage and dentary bone; op, opercule; pq, palatoquadrate. Scale bars: in J, 100 μm for A,D,G,J; in K, 100 μm for B,E,H,K; in L, 100 μm for C,F,I,L.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	sox9a^tw37/tw37 + MO2-sox9a + MO3-sox9a WT + MO2-sox9a + MO3-sox9a sox9a^tw37/+ + MO2-sox9a + MO3-sox9a
Knockdown Reagents:	MO2-sox9a MO3-sox9a
Observed In:	basihyal cartilage cartilage development ceratobranchial bone ceratohyal cartilage cleithrum hyosymplectic cartilage Meckel's cartilage palatoquadrate cartilage pectoral fin endoskeletal disc scapulocoracoid (all 10)
Stage:	Day 5

Phenotype Detail

Acknowledgments

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