FIGURE

Fig. S1

ID

ZDB-FIG-061219-8

Publication

Mendelsohn et al., 2006 - Atp7a determines a hierarchy of copper metabolism essential for notochord development

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Fig. S1

Alignment of amino acid sequence of human and zebrafish atp7a Sequence alignment reveals 64.5% identity with marked conservation of CPC copper transport domain (underlined in black), all 6 MXCXXC copper-binding motifs (underlined in red), the invariant aspartate (underlined in blue) and the conserved SEHPL sequence required for trafficking (underlined in green).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Cell Metabolism, 4(2), Mendelsohn, B.A., Yin, C., Johnson, S.L., Wilm, T.P., Solnica-Krezel, L., and Gitlin, J.D., Atp7a determines a hierarchy of copper metabolism essential for notochord development, 155-162, Copyright (2006) with permission from Elsevier. Full text @ Cell Metab.