FIGURE

Fig. 4

ID

ZDB-FIG-060201-5

Publication

Hamade et al., 2006 - Retinoic acid activates myogenesis in vivo through Fgf8 signalling

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Fig. 4

Somite maturation but not segmentation pattern is regulated by RA. 15-somite (A?C) and 10-somite (D?L) stage embryos are displayed as in Fig. 2. (A?C) At the 15-somite stage, twist is expressed in sclerotome. twist expression is reduced in DEAB-treated embryos (B) and increased in RA-treated embryos (C). (D?I) The segmented pattern (arrows) of mesp-b (D?F) and papc (G?I) is not modified by either DEAB or RA treatments. (J?L) paraxis is expressed in anterior psm (bracket) and somites. Expression of paraxis in DEAB-treated embryos is similar to that in control (K) while it is extended posteriorly in RA-treated embryos (L; bracket). Scale bars: in panel A, 100 μm for panels A?C; in panel D, 100 μm for panels D?L.

Expression Data

Genes:	mespba pcdh8 tcf15
Fish:	WT
Conditions:	chemical treatment by environment: 4-(diethylamino)benzaldehyde chemical treatment: all-trans-retinoic acid
Anatomical Terms:	segmental plate somite
Stage:	10-13 somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 289(1), Hamade, A., Deries, M., Begemann, G., Bally-Cuif, L., Genet, C., Sabatier, F., Bonnieu, A., and Cousin, X., Retinoic acid activates myogenesis in vivo through Fgf8 signalling, 127-140, Copyright (2006) with permission from Elsevier. Full text @ Dev. Biol.