| ZFIN ID: ZDB-EXP-171108-12 |
Experiment Conditions Description: chemical treatment by environment: granisetron, chemical treatment by environment: fluoxetine
| chemical treatment by environment: granisetron |
|---|
| Name: | chemical treatment by environment |
|---|---|
| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | granisetron |
|---|---|
| Synonyms: | 1-methyl-N-(9-methyl-endo-9-azabicyclo(3.3.1)non-3-yl)-1H-indazole-3-carboxamide, 1-methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide, APF 530, APF530, BRL 43694, granisetron, granisetronum, Kevatril, Sancuso, Sustol |
| Definition: | A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of 1-methyl-1H-indazole-3-carboxylic acid with the primary amino group of (3-endo)-9-methyl-9-azabicyclo[3.3.1]nonan-3-amine. A selective 5-HT3 receptor antagonist, it is used (generally as the monohydrochloride salt) to manage nausea and vomiting caused by cancer chemotherapy and radiotherapy, and to prevent and treat postoperative nausea and vomiting. |
| Ontology: | ChEBI [CHEBI:5537] ( EBI ) |
| chemical treatment by environment: fluoxetine |
|---|
| Name: | chemical treatment by environment |
|---|---|
| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | fluoxetine |
|---|---|
| Synonyms: | (+-)-N-methyl-3-phenyl-3-((alpha,alpha,alpha-trifluoro-p-tolyl)oxy)propylamine, (+-)-N-methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine, fluoxetina, fluoxetine, fluoxetinum, Prozac, rac-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine |
| Definition: | A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder. |
| Ontology: | ChEBI [CHEBI:5118] ( EBI ) |
| Publication: | Kwaku Benneh et al., 2017 |
|---|