fluoxetine

Term ID

CHEBI:5118

Synonyms

• (+-)-N-methyl-3-phenyl-3-((alpha,alpha,alpha-trifluoro-p-tolyl)oxy)propylamine
• (+-)-N-methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine
• fluoxetina
• fluoxetine
• fluoxetinum
• Prozac
• rac-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine

Definition

A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.

References

• beilstein:39914106
• cas:54910-89-3
• drugbank:DB00472
• hmdb:HMDB0014615
• kegg.drug:D00326
• patent:DE2500110
• patent:US4314081
• pubmed:19144769
• pubmed:22903652
• pubmed:22923967
• pubmed:23885544
• pubmed:24184049
• pubmed:24399719
• pubmed:24464553
• pubmed:24997906
• pubmed:25448156
• pubmed:25639887
• pubmed:25671301
• pubmed:8694321
• reaxys:3991406
• wikipedia.en:Fluoxetine

Ontology

ChEBI  ( EBI )

Resources

CTD