Search Ontology:
ChEBI

granisetron

Term ID
CHEBI:5537
Synonyms
  • 1-methyl-N-(9-methyl-endo-9-azabicyclo(3.3.1)non-3-yl)-1H-indazole-3-carboxamide
  • 1-methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide
  • APF 530
  • APF530
  • BRL 43694
  • granisetron
  • granisetronum
  • Kevatril
  • Sancuso
  • Sustol
Definition
A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of 1-methyl-1H-indazole-3-carboxylic acid with the primary amino group of (3-endo)-9-methyl-9-azabicyclo[3.3.1]nonan-3-amine. A selective 5-HT3 receptor antagonist, it is used (generally as the monohydrochloride salt) to manage nausea and vomiting caused by cancer chemotherapy and radiotherapy, and to prevent and treat postoperative nausea and vomiting.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from granisetron
Phenotype where environments contain granisetron
Phenotype modified by environments containing granisetron
Human Disease / Model Data