CRISPR

CRISPR8-gdf11

ID
ZDB-CRISPR-260930-2
Name
CRISPR8-gdf11
Previous Names
None
Target
Sequence
5' - TCCTGAAGGCGCAGCTTT - 3'
ZFIN BLAST NCBI BLAST Ensembl
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
zf4391 gdf11
Expression
Gene expression in Wild Types + CRISPR8-gdf11
No data available
Phenotype
Phenotype resulting from CRISPR8-gdf11
No data available
Phenotype of all Fish created by or utilizing CRISPR8-gdf11
Phenotype Fish Conditions Figures
pronephric duct apoptotic process decreased process quality, abnormal gdf11zf4391/zf4391 (AB) standard conditions Fig. 4 with image from Tian et al., 2025
pronephric duct dilated, abnormal gdf11zf4391/zf4391 (AB) control Fig. 2 with image from Tian et al., 2025
cloaca excretion decreased process quality, abnormal gdf11zf4391/zf4391 (AB) control Fig. 1 with image from Tian et al., 2025
pronephric tubule dilated, abnormal gdf11zf4391/zf4391 (AB) control Fig. 2 with image from Tian et al., 2025
pronephric tubule ab1-tuba labeling decreased distribution, abnormal gdf11zf4391/zf4391 (AB) control Fig. 5 with image from Tian et al., 2025
vent decreased width, abnormal gdf11zf4391/zf4391 (AB) standard conditions Fig. 1 with image from Tian et al., 2025
cloaca morphology, abnormal gdf11zf4391/zf4391 (AB) standard conditions Fig. 1 with image from Tian et al., 2025
intermediate mesoderm cdh17 expression decreased distribution, abnormal gdf11zf4391/zf4391 (AB) standard conditions Fig. 2 with image from Tian et al., 2025
pronephros decreased width, abnormal gdf11zf4391/zf4391 (AB) control Fig. 2 with image from Tian et al., 2025
cloaca apoptotic process decreased process quality, abnormal gdf11zf4391/zf4391 (AB) standard conditions Fig. 4 with image from Tian et al., 2025
pronephric distal late tubule slc12a3 expression decreased distribution, abnormal gdf11zf4391/zf4391 (AB) standard conditions Fig. 2 with image,  Fig. 5 with image from Tian et al., 2025
cloaca decreased width, abnormal gdf11zf4391/zf4391 (AB) standard conditions Fig. 1 with image from Tian et al., 2025
pronephric glomerulus nphs1 expression decreased distribution, abnormal gdf11zf4391/zf4391 (AB) standard conditions Fig. 2 with image from Tian et al., 2025
pronephric tubule cilium decreased distribution, abnormal gdf11zf4391/zf4391 (AB) control Fig. 2 with image from Tian et al., 2025
pronephric glomerulus wt1a expression decreased distribution, abnormal gdf11zf4391/zf4391 (AB) standard conditions Fig. 2 with image from Tian et al., 2025
cloaca evx1 expression decreased distribution, abnormal gdf11zf4391/zf4391 (AB) standard conditions Fig. 2 with image,  Fig. 5 with image from Tian et al., 2025
intermediate mesoderm pax2a expression decreased distribution, abnormal gdf11zf4391/zf4391 (AB) standard conditions Fig. 2 with image from Tian et al., 2025
pronephric proximal convoluted tubule slc4a4a expression decreased distribution, abnormal gdf11zf4391/zf4391 (AB) standard conditions Fig. 2 with image,  Fig. 5 with image from Tian et al., 2025
cloaca ab1-prkcz labeling spatial pattern, ameliorated gdf11zf4391/zf4391 (AB) standard conditions Fig. 1 with image from Tian et al., 2025
pronephric distal early tubule trpm7 expression decreased distribution, abnormal gdf11zf4391/zf4391 (AB) standard conditions Fig. 2 with image,  Fig. 5 with image from Tian et al., 2025
pronephric glomerulus decreased size, abnormal gdf11zf4391/zf4391 (AB) control Fig. 2 with image from Tian et al., 2025
pronephric tubule cilium ab1-tuba labeling decreased distribution, abnormal gdf11zf4391/zf4391 (AB) standard conditions Fig. 2 with image from Tian et al., 2025
cloaca prdm1a expression decreased distribution, abnormal gdf11zf4391/zf4391 (AB) standard conditions Fig. 2 with image,  Fig. 5 with image from Tian et al., 2025
pronephros pax2a expression decreased distribution, abnormal gdf11zf4391/zf4391 (AB) standard conditions Fig. 2 with image from Tian et al., 2025
pronephric duct DsRed expression decreased distribution, abnormal gdf11zf4391/zf4391; zf4392Tg (AB) standard conditions Fig. 2 with image from Tian et al., 2025
pronephric tubule DsRed expression decreased distribution, abnormal gdf11zf4391/zf4391; zf4392Tg (AB) standard conditions Fig. 2 with image from Tian et al., 2025
Citations
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