CRISPR

CRISPR1-mc2r

ID

ZDB-CRISPR-260403-2

Name

CRISPR1-mc2r

Previous Names

None

Target

mc2r (1)

Sequence

5' - GGTGTTTCTGGTCATCGCAG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
iim23	mc2r
iim24	mc2r

Expression

Gene expression in Wild Types + CRISPR1-mc2r

No data available

Phenotype

Phenotype resulting from CRISPR1-mc2r

No data available

Phenotype of all Fish created by or utilizing CRISPR1-mc2r

Phenotype	Fish	Conditions	Figures
integument iridophore alx4b expression increased amount, abnormal	mc2r^iim23/iim23 (TU)	standard conditions	Fig. 6 from Barreiro-Docío et al., 2026
integument xanthophore increased amount, abnormal	mc2r^iim23/iim23 (TU)	standard conditions	Fig. 4 from Barreiro-Docío et al., 2026
integument melanocyte tyrp1b expression increased amount, abnormal	mc2r^iim23/iim23 (TU)	standard conditions	Fig. 6 from Barreiro-Docío et al., 2026
integument xanthophore pax7b expression increased amount, abnormal	mc2r^iim23/iim23 (TU)	standard conditions	Fig. 6 from Barreiro-Docío et al., 2026
melanophore stripe increased pigmentation, abnormal	mc2r^iim23/iim23 (TU)	standard conditions	Fig. 3 from Barreiro-Docío et al., 2026
integument xanthophore slc2a15a expression increased amount, abnormal	mc2r^iim23/iim23 (TU)	standard conditions	Fig. 6 from Barreiro-Docío et al., 2026
integument iridophore sox10 expression increased amount, abnormal	mc2r^iim23/iim23 (TU)	standard conditions	Fig. 6 from Barreiro-Docío et al., 2026
integument xanthophore aox5 expression increased amount, abnormal	mc2r^iim23/iim23 (TU)	standard conditions	Fig. 6 from Barreiro-Docío et al., 2026
integument melanocyte csnk1a1 expression decreased amount, abnormal	mc2r^iim23/iim23 (TU)	standard conditions	Fig. 6 from Barreiro-Docío et al., 2026
integument xanthophore bscl2l expression increased amount, abnormal	mc2r^iim23/iim23 (TU)	standard conditions	Fig. 6 from Barreiro-Docío et al., 2026
integument iridophore tpd52l1 expression decreased amount, abnormal	mc2r^iim23/iim23 (TU)	standard conditions	Fig. 6 from Barreiro-Docío et al., 2026
integument iridophore foxd3 expression increased amount, abnormal	mc2r^iim23/iim23 (TU)	standard conditions	Fig. 6 from Barreiro-Docío et al., 2026
whole organism cortisol amount, ameliorated	mc2r^iim23/iim23 (TU)	stress	Fig. 2 from Barreiro-Docío et al., 2026
integument xanthophore plin6 expression increased amount, abnormal	mc2r^iim23/iim23 (TU)	standard conditions	Fig. 6 from Barreiro-Docío et al., 2026
integument iridophore adssl expression decreased amount, abnormal	mc2r^iim23/iim23 (TU)	standard conditions	Fig. 6 from Barreiro-Docío et al., 2026
melanophore stripe melanocyte increased amount, abnormal	mc2r^iim23/iim23 (TU)	standard conditions	Fig. 4 from Barreiro-Docío et al., 2026
dermis mc2r expression decreased amount, abnormal	mc2r^iim23/iim23 (TU)	standard conditions	Fig. 1 from Barreiro-Docío et al., 2026
integument melanocyte tyr expression increased amount, abnormal	mc2r^iim23/iim23 (TU)	standard conditions	Fig. 6 from Barreiro-Docío et al., 2026
integument melanocyte pmela expression increased amount, abnormal	mc2r^iim23/iim23 (TU)	standard conditions	Fig. 6 from Barreiro-Docío et al., 2026
integument xanthophore bco2b expression decreased amount, abnormal	mc2r^iim23/iim23 (TU)	standard conditions	Fig. 6 from Barreiro-Docío et al., 2026
whole organism cortisol amount, ameliorated	mc2r^iim23/iim23 (TU)	chemical treatment by injection: corticotropin	Fig. 2 from Barreiro-Docío et al., 2026
integument iridophore zic2a expression increased amount, abnormal	mc2r^iim23/iim23 (TU)	standard conditions	Fig. 6 from Barreiro-Docío et al., 2026
integument melanocyte pah expression increased amount, abnormal	mc2r^iim23/iim23 (TU)	standard conditions	Fig. 6 from Barreiro-Docío et al., 2026
integument melanocyte mlpha expression increased amount, abnormal	mc2r^iim23/iim23 (TU)	standard conditions	Fig. 6 from Barreiro-Docío et al., 2026

Citations